State Veterinarian Dustin Oedekoven has confirmed that eight cows died out of a herd of 87 unvaccinated cattle in Clark County.
The Animal Disease Research and Diagnostic Laboratory at South Dakota State University confirmed the disease from samples submitted over the weekend.
Anthrax can cause the rapid loss of a large number of animals in a short time. Infected livestock often are found dead with no illness detected.
The South Dakota Animal Industry Board says anthrax spores survive indefinitely in contaminated soil. The board says strict enforcement of quarantines and proper burning and burying of carcasses suspected to have died from anthrax is important to prevent further soil contamination from bacterial spores.
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Officials say anthrax has been confirmed in South Dakota livestock for the first time year this year.